SYNTHESIS OF 1-N-ACYL DERIVATIVES OF 3', 4'-DIDEOXY-6'-N-METHYL-KANAMYCIN-B AND THEIR ANTIBACTERIAL ACTIVITIES

被引：5

作者：

UMEZAWA, H ^{[1
]}

IINUMA, K ^{[1
]}

KONDO, S ^{[1
]}

HAMADA, M ^{[1
]}

MAEDA, K ^{[1
]}

机构：

[1] INST MICROBIAL CHEM,KAMIOSAKI,SHINAGAWA,TOKYO,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1975年 / 28卷 / 04期

关键词：

D O I：

10.7164/antibiotics.28.340

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：340 / 343

页数：4

共 14 条

[1] SYNTHESES OF 1-N-[(S)-4-AMINO-2-HYDROXYBUTYRYL]-KANAMYCIN B AND -3', 4'-DIDEOXYKANAMYCIN B ACTIVE AGAINST KANAMYCIN-RESISTANT BACTERIA [J].

KONDO, S ;

IINUMA, K ;

YAMAMOTO, H ;

MAEDA, K ;

UMEZAWA, H .

JOURNAL OF ANTIBIOTICS, 1973, 26 (07) :412-415

[2] SYNTHESES OF ISOSERYL DERIVATIVES OF KANAMYCINS AND THEIR ANTIBACTERIAL ACTIVITIES [J].

KONDO, S ;

IINUMA, K ;

HAMADA, M ;

MAEDA, K ;

UMEZAWA, H .

JOURNAL OF ANTIBIOTICS, 1974, 27 (01) :90-93

[3] SYNTHESES OF (S)-4-AMINO-2-HYDROXYBUTYRYL DERIVATIVES OF 3',4'-DIDEOXYKANAMYCIN-B AND THEIR ANTIBACTERIAL ACTIVITIES [J].

KONDO, S ;

IINUMA, K ;

YAMAMOTO, H ;

IKEDA, Y ;

MAEDA, K ;

UMEZAWA, H .

JOURNAL OF ANTIBIOTICS, 1973, 26 (11) :705-707

[4] STRUCTURE DETERMINATION OF AN ENZYMATIC INACTIVATION PRODUCT OF 3',4'-DIDEOXYKANAMYCIN-B [J].

NAGANAWA, H ;

YAGISAWA, M ;

KONDO, S ;

TAKEUCHI, T ;

UMEZAWA, H .

JOURNAL OF ANTIBIOTICS, 1971, 24 (12) :913-&

[5] NEW AGENTS FOR TERTIARY BUTYLOXYCARBONYLATION AND PARA METHOXYBENZYL-OXYCARBONYLATION OF AMINO-ACIDS [J].

NAGASAWA, T ;

KUROIWA, K ;

NARITA, K ;

ISOWA, Y .

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1973, 46 (04) :1269-1272

[6]

OHSHIRO S, 1967, Yakugaku Zasshi, V87, P1184

[7]

UMEZAWA H, 1967, SCIENCE, V157, P1559

[8] 3',4'-DIDEOXY-KANAMYCIN B ACTIVE AGAINST KANAMYCIN-RESISTANT ESCHERICHIA-COLI AND PSEUDOMONAS-AERUGINOSA [J].

UMEZAWA, H ;

UMEZAWA, S ;

TSUCHIYA, T ;

OKAZAKI, Y .

JOURNAL OF ANTIBIOTICS, 1971, 24 (07) :485-&

[9] KANAMYCIN PHOSPHOTRANSFERASE .1. MECHANISM OF CROSS RESISTANCE BETWEEN KANAMYCIN AND LIVIDOMYCIN [J].

UMEZAWA, H ;

YAMAMOTO, H ;

YAGISAWA, M ;

KONDO, S ;

TAKEUCHI, T ;

CHABBERT, YA .

JOURNAL OF ANTIBIOTICS, 1973, 26 (07) :407-411

[10] SYNTHESES OF 6'-N-METHYL-KANAMYCIN AND 3',4'-DIDEOXY-6'-N-METHYLKANAMYCIN B ACTIVE AGAINST RESISTANT STRAINS HAVING 6'-N-ACETYLATING ENZYMES [J].

UMEZAWA, H ;

NISHIMURA, Y ;

TSUCHIYA, T ;

UMEZAWA, S .

JOURNAL OF ANTIBIOTICS, 1972, 25 (12) :743-745

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