IMMUNOLOGICAL STUDIES OF INSOLUBLE LIPOPROTEINS .2. ON SALIVARY GLAND-CHARACTERISTIC ANTIGENS

被引：10

作者：

KURATA, Y

WATANABE, Y

OKADA, S

FUKUYAMA, Y

机构：

[1] Department of Pathophysiology, Cancer Research Institute, Kanazawa University, Kanazawa

来源：

INTERNATIONAL ARCHIVES OF ALLERGY AND APPLIED IMMUNOLOGY | 1969年 / 35卷 / 04期

关键词：

D O I：

10.1159/000230191

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

It was shown that the hetero- and homoimmunization of guinea pigs with insoluble lipoprotein (LP) of the parotid or submaxillary glands in Freund adjuvant was successful in producing positive skin reacrions, precipitating autoantibodies and definite histological lesions mainly in the parotid glands. Two antigens detected with the anti-salivary gland LP sera were of considerable organ-specificity, the largest amounts being confined to the parotid and submaxillary gland. The antigens were solubilized by treatment with desoxycholate and partially purified by gel filtration on Sepharose 4B. © 1969 S. Karger AG, Basel.

引用

页码：392 / &

共 9 条

[1]

ANDERSON JR, 1967, AUTIMMUNITY CLINICAL, P458

[2] A SPECIFIC ANTIBODY AGAINST EPITHELIUM OF SALIVARY DUCTS IN SERA FROM PATIENTS WITH SJOGRENS SYNDROME [J].