INDUCTION OF MEMBRANE PROLIFERATION IN MOUSE CNS BY GOLD SODIUM THIOMALATE WITH REFERENCE TO INCREASED VIRULENCE OF THE AVIRULENT SEMLIKI FOREST VIRUS

被引：12

作者：

MEHTA, S

PATHAK, S

WEBB, HE

机构：

[1] Neurovirology Unit, Rayne Institute, The United Medical and Dental Schools of Guy's and St. Thomas' Hospital, St. Thomas' Hospital, London

来源：

BIOSCIENCE REPORTS | 1990年 / 10卷 / 03期

关键词：

gold sodium thiomalate; membrane proliferation; SFV;

D O I：

10.1007/BF01117243

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Separation of smooth membrane vesicles from whole mouse brain by isopycnic centrifugation in discontinuous sucrose density gradients show an increased membrane proliferation in gold sodium thiomalate (GSTM) treated mice. Induction of membrane proliferation by GSTM seems to be an important factor in converting the avirulent Semliki Forest virus infection into a lethal one. © 1990 Plenum Publishing Corporation.

引用

页码：271 / 279

页数：9

共 18 条

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