GENETIC POLYMORPHISMS AND INTRA-UTERINE DEVELOPMENT - EVIDENCE OF DECREASED HETEROZYGOSITY IN LIGHT-FOR-DATES HUMAN NEWBORN BABIES

被引：31

作者：

BOTTINI, E

GLORIABOTTINI, F

LUCARELLI, P

POLZONETTI, A

SANTORO, F

VARVERI, A

机构：

[1] UNIV CAMERINO,CTR COMP,I-62032 CAMERINO,ITALY

[2] CNR,CTR EVOLUTIONARY GENET,ROME,ITALY

[3] BAMBINO GESU HOSP SICK CHILDREN,ROME,ITALY

来源：

EXPERIENTIA | 1979年 / 35卷 / 12期

关键词：

D O I：

10.1007/BF01953195

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

In 2 independent samples of low-birth-weight infants the proportion of females and homozygotes for a series of polymorphic systems was higher in light-for-dates than in preterm babies. The observation seems to give support to the hypothesis that homozygosity for 'normal' polymorphisms may decrease in general intrauterine growth rate. Since it is known that survival rate is strongly related to birth weight, a correlation between growth retardation and homozygosity may have a major role in the maintenance of such polimorphisms. © 1979 Birkhäuser Verlag.

引用

页码：1565 / 1567

页数：3