DOUBLE-BLIND, PLACEBO-CONTROLLED, CROSS-OVER STUDY OF FLAVOXATE IN THE TREATMENT OF IDIOPATHIC DETRUSOR INSTABILITY

被引:44
作者
CHAPPLE, CR
PARKHOUSE, H
GARDENER, C
MILROY, EJG
机构
[1] Department of Urology, Middlesex Hospital, London
来源
BRITISH JOURNAL OF UROLOGY | 1990年 / 66卷 / 05期
关键词
D O I
10.1111/j.1464-410X.1990.tb14994.x
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Summary— Detrusor instability occurs in approximately 10% of the adult population, producing troublesome symptoms. The pharmacotherapy currently available is usually only partially effective and cannot be adequately evaluated except under “blind” conditions because of the significant component attributable to placebo effects. The results of the present study revealed no advantage resulting from treatment with flavoxate, as assessed both subjectively and objectively. We suggest that this therapy does not appear to be beneficial in the medical management of detrusor instability. © 1990 British Journal of Urology
引用
收藏
页码:491 / 494
页数:4
相关论文
共 6 条
[1]   THE EFFECT OF FLAVOXATE ON UNINHIBITED DETRUSOR CONTRACTIONS AND URINARY-INCONTINENCE IN THE ELDERLY [J].
BRIGGS, RS ;
CASTLEDEN, CM ;
ASHER, MJ .
JOURNAL OF UROLOGY, 1980, 123 (05) :665-666
[2]  
FANGLUI G, 1987, J INT MED RES, V153, P312
[3]  
GRAZIANI G, 1983, FLAVOXATE, P7
[4]   2-PERIOD CROSSOVER CLINICAL-TRIAL [J].
HILLS, M ;
ARMITAGE, P .
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1979, 8 (01) :7-20
[5]  
RUFFMANN R, 1987, DRUG EXP CLIN RES, V13, P57
[6]   COMPARISON OF EMEPRONIUM BROMIDE AND FLAVOXATE HYDROCHLORIDE IN TREATMENT OF URINARY INCONTINENCE [J].
STANTON, SL .
JOURNAL OF UROLOGY, 1973, 110 (05) :529-532