CORD BLOOD IGE .1. IGE SCREENING IN 2814 NEWBORN CHILDREN

被引：36

作者：

HANSEN, LG

HOST, A

HALKEN, S

HOLMSKOV, A

HUSBY, S

LASSEN, LB

STORM, K

OSTERBALLE, O

机构：

[1] VIBORG HOSP,DEPT PEDIAT,DK-8800 VIBORG,DENMARK

[2] VIBORG HOSP,DEPT GYNECOL & OBSTET,DK-8800 VIBORG,DENMARK

[3] ODENSE UNIV HOSP,DEPT PEDIAT,DK-5000 ODENSE,DENMARK

来源：

ALLERGY | 1992年 / 47卷 / 04期

关键词：

ATOPY; CORD SERUM; IGE; NEWBORN; PREDICTION; SCREENING;

D O I：

10.1111/j.1398-9995.1992.tb02078.x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Screening of total IgE in 2814 cord blood samples was analysed by Phadebas IgE PRIST in 2 1-year birth cohorts (1983-1984 and 1985-1986) in Denmark (n = 1189 + 1625). 48.6% of the sera contained less IgE than the detection limit 0.1 kU/l. Cord blood IgE values greater-than-or-equal-to 0. 5 kU/I were regarded as elevated. 13.2% of the sera contained at least 0.5 kU/l of IgE, with a significant preponderance in boys. Geometric mean cord blood IgE was 0.13 kU/l and 0.12 kU/l, respectively. Geometric mean cord blood IgE was significantly higher in boys. A significant seasonal variation with lowest IgE values in the autumn was found. No correlation between cord blood IgE and birth weight or gestational age was demonstrated. Only few newborns had cord blood IgA values > 0.014 g/l, calculated as geometric mean cord blood IgA + 2 SD among children with no detectable cord blood IgE, indicating infrequent contamination with maternal blood.

引用

页码：391 / 396

页数：6

共 38 条

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