RECOGNITION OF SIALIC-ACID USING MOLECULARLY IMPRINTED POLYMER

被引：32

作者：

KUGIMIYA, A

MATSUI, J

TAKEUCHI, T

YANO, K

MUGURUMA, H

ELGERSMA, AV

KARUBE, I

机构：

[1] UNIV TOKYO,ADV SCI & TECHNOL RES CTR,MEGURO KU,TOKYO 153,JAPAN

[2] HIROSHIMA CITY UNIV,FAC INFORMAT SCI,ASAMINAMI KU,HIROSHIMA 73131,JAPAN

来源：

ANALYTICAL LETTERS | 1995年 / 28卷 / 13期

关键词：

MOLECULAR IMPRINTING; SIALIC ACID; SUGAR; LIQUID CHROMATOGRAPHY;

D O I：

10.1080/00032719508000375

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The molecular imprinting technique was applied for the preparation of a polymer selective for sialic acid. To evaluate its binding ability the molecularly imprinted polymer obtained was used as a stationary phase in liquid chromatography. The polymer showed pH-dependent characteristics for binding: an optimum specificity to sialic acid at pH 8.1 and a higher affinity with group selectivity for cis-diol containing sugars at higher pH.

引用

页码：2317 / 2323

页数：7

共 9 条

[1]

HERRLER G, 1992, J BIOL CHEM, V267, P12501

[2] ARYLBORONIC ACIDS .3. PREPARATION AND POLYMERIZATION OF PARA-VINYLBENZENEBORONIC ACID [J].