IODINE, A PROTECTING GROUP FOR THE SYNTHESIS OF PSORALEN DERIVATIVES OXYGENATED IN PYRONE RING - SYNTHESIS OF 4,5-DIMETHOXYPSORALEN AND 3,4,5-TRIMETHOXYPSORALEN (HALFORDIN)

被引：11

作者：

AHLUWALIA, VK

PRAKASH, C

SINGH, RP

机构：

[1] Department of Chemistry, University of Delhi, Delhi

来源：

TETRAHEDRON | 1979年 / 35卷 / 17期

关键词：

D O I：

10.1016/S0040-4020(01)88984-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient synthesis of psoralen derivatives oxygenated in pyrone ring, viz 4,5-dimethoxy-7-oxo-7H-furo [3,2-g] [1] benzopyran (4,5-dimethoxypsoralen) and 4,5,6-trimethoxy-7-oxo-7H-furo [3,2-g] [1] benzopyran (halfordin) (3,4,5-trimethoxypsoralen) is described by blocking the 8-position with iodine, Claisen migration followed by cyclisation. © 1979.

引用

页码：2081 / 2085

页数：5

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