DIABETIC GLOMERULOSCLEROSIS WITHOUT DIABETES-MELLITUS - 2 CASE-REPORTS AND A REVIEW OF THE LITERATURE

被引：22

作者：

INNES, A ^{[1
]}

FURNESS, PN ^{[1
]}

COTTON, RE ^{[1
]}

BURDEN, RP ^{[1
]}

MORGAN, AG ^{[1
]}

机构：

[1] CITY HOSP,DEPT HISTOPATHOL,NOTTINGHAM NG5 1PB,ENGLAND

来源：

NEPHROLOGY DIALYSIS TRANSPLANTATION | 1992年 / 7卷 / 07期

关键词：

KIMMELSTIEL-WILSON NODULES; WITHOUT DIABETES-MELLITUS;

D O I：

10.1093/ndt/7.7.642

中图分类号：

R3 [基础医学]; R4 [临床医学];

学科分类号：

1001 ; 1002 ; 100602 ;

摘要：

The duration of diabetes mellitus and presence of hyperglycaemia appear to be important in the development of diabetic nephropathy. The presence of nodular glomerulosclerosis is thought to be pathognomonic of the condition. We report two patients with histological features of diabetic glomerulosclerosis who did not have diabetes mellitus. The discussion reviews the literature and concludes that diabetic glomerulosclerosis with normal glucose tolerance is very rare and that most cases are due to overt diabetes mellitus or a degree of glucose intolerance. However, cases with only minimal glucose intolerance suggest that factor(s) other than hyperglycaemia are responsible for diabetic renal damage.

引用

页码：642 / 646

页数：5

共 19 条

[1]

ANDERSEN AR, 1983, DIABETOLOGIA, V25, P496

[2] SEVERE DIABETIC MICRO-ANGIOPATHY WITH NORMAL GLUCOSE-TOLERANCE AND PITUITARY INFARCTION [J].