CHARACTERIZATION OF 4-AMINOPYRIDINE IN OVERDOSE

被引:48
作者
STORK, CM [1 ]
HOFFMAN, RS [1 ]
机构
[1] BELLEVUE HOSP CTR,NEW YORK,NY 10016
来源
JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY | 1994年 / 32卷 / 05期
关键词
AMINOPYRIDINE; POISONING; HUMAN;
D O I
10.3109/15563659409011063
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
We report three cases of 4-aminopyridine overdose resulting in seizure activity. All patients were on therapeutic regimens for the treatment of multiple sclerosis. All patients were responsive to intensive supportive care, although the length of toxicity was prolonged more than 24 hours in one patient. Seizure activity was responsive to benzodiazepine and phenytoin therapy.
引用
收藏
页码:583 / 587
页数:5
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