POTASSIUM CORTICOSTERONE AND ADRENOCORTICOTROPIC HORMONE RELEASE IN VITRO

被引：16

作者：

KRAICER, J

MILLIGAN, JV

GOSBEE, JL

CONRAD, RG

BRANSON, CM

机构：

[1] Department of Physiology, Queen's University, Kingston, Ont.

来源：

SCIENCE | 1969年 / 164卷 / 3878期

关键词：

D O I：

10.1126/science.164.3878.426

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Incubation of rat adenohypophyses in a high concentration of potassium increases adrenocorticotropic hormone release. This increased release is suppressed by the addition of corticosterone to the incubating medium. Our findings are consistent with a process of stimulus-secretion coupling" proposed for other glands and suggest that corticosterone may operate directly on the adenohypophysial cell membrane to inhibit releasing mechanisms."

引用

页码：426 / &

共 9 条

[1] Boyle PJ, 1941, J PHYSIOL-LONDON, V100, P1
[2] DOUGLAS WW, 1967, NEUROSECRETION, P178
[3] EISENSTEIN AB, 1967, ADRENAL CORTEX ED, P133
[4] INVITRO BIOASSAY OF CORTICOTROPIN - MODIFICATION AND STATISTICAL TREATMENT
SAFFRAN, M
SCHALLY, AV
[J]. ENDOCRINOLOGY, 1955, 56 (05) : 523 - 532
[5] SALMI MH, 1968, ENDOCRINOLOGY, V82, P225
[6] STUTINSKY F, 1967, NEUROSCRETION ED, P178
[7] UMBREIT WW, 1964, MANOMETRIC TECHNIQUE, P132
[8] POTASSIUM-INDUCED STIMULATION OF THYROTROPIN RELEASE IN VITRO - REQUIREMENT FOR PRESENCE OF CALCIUM AND INHIBITION BY THYROXINE
VALE, W
GUILLEMIN, R
[J]. EXPERIENTIA, 1967, 23 (10): : 855 - +
[9] YATES F. EUGENE, 1967, P133

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