THE PROMOTER AND 1ST, UNTRANSLATED EXON OF THE HUMAN GLUCOCORTICOID RECEPTOR GENE ARE GC RICH BUT LACK CONSENSUS GLUCOCORTICOID RECEPTOR ELEMENT SITES

被引：98

作者：

ZONG, J ^{[1
]}

ASHRAF, J ^{[1
]}

THOMPSON, EB ^{[1
]}

机构：

[1] UNIV TEXAS, MED BRANCH, DEPT HUMAN BIOL CHEM & GENET, GALVESTON, TX 77550 USA

来源：

MOLECULAR AND CELLULAR BIOLOGY | 1990年 / 10卷 / 10期

关键词：

D O I：

10.1128/MCB.10.10.5580

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Glucocorticoid receptor mRNA is regulated by glucocorticoids. We found no consensus glucocorticoid response element, TATA box, or CAAT box but many GC boxes in ~3 kilobases of the 5'-flanking sequence of the human glucocorticoid receptor gene. We identified several transcription start sites, an untranslated exon 1, and the coding content of exon 2.

引用

页码：5580 / 5585

页数：6

共 44 条

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