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SYNTHESIS OF 3 NEW CARBOCYCLIC ANALOGS OF 3'-DEOXY PURINE RIBONUCLEOSIDES

被引：11
作者：
AGROFOGLIO, L
CONDOM, R
GUEDJ, R
CHALLAND, SR
SELWAY, J
机构：
[1] FAC SCI NICE,UNSA,CHIM BIOORGAN LAB,BP 71F,F-06108 NICE 02,FRANCE
[2] WELLCOME RES LABS,BECKENHAM BR3 3BS,KENT,ENGLAND
来源：
NUCLEOSIDES & NUCLEOTIDES | 1994年 / 13卷 / 05期
关键词：
D O I：
10.1080/15257779408011885
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The 1-hydroxymethyl-3-cyclopentene (4) was converted, after epoxidation, to two new exocyclic amino carbocyclic nucleosides (1, 2), and a new cyclopentane nucleoside analogue (3), with potential biological activities. The regioselectivity of the epoxidation (4), which is the key step, is governed by steric control using aryl and silyl hydroxyl protecting groups.
引用
收藏
页码：1147 / 1160
页数：14
相关论文
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