NORMAL SURAL NERVE IN MAN .2. CHANGES IN AXONS AND SCHWANN CELLS DUE TO AGEING

被引：282

作者：

OCHOA, J

MAIR, WGP

机构：

[1] The Institute of Neurology, London, W.C.1, Queen Square

来源：

ACTA NEUROPATHOLOGICA | 1969年 / 13卷 / 03期

关键词：

Nerve Degeneration; Nerve Regeneration Ageing; Peripheral Nerves;

D O I：

10.1007/BF00690643

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

In a combined light and electron microscope study of sural nerves of seven normal individuals, aged between 15 and 59 years, the increase with age in the number of degenerating myelinated fibres is confirmed. Destruction of unmyelinated fibres starting early in life is reported for the first time. The sequence of events in the involution of unmyelinated fibres was found to be the budding of their Schwann cells followed by increasing evidence of their denervation and axonal sprouting. Comments are made on the value of several direct and indirect indices of destruction of nerve fibres. The relevance of denervation and regeneration of fibres in assessing pathological change in slowly progressive disorders of peripheral nerves is emphasised. © 1969 Springer-Verlag.

引用

页码：217 / +

页数：1

共 103 条

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