A NEW DEPSIPEPTIDE ANTIBIOTIC, VARIAPEPTIN

被引：20

作者：

NAKAGAWA, M ^{[1
]}

HAYAKAWA, Y ^{[1
]}

ADACHI, K ^{[1
]}

SETO, H ^{[1
]}

机构：

[1] UNIV TOKYO,INST APPL MICROBIOL,BUNKYO KU,TOKYO 113,JAPAN

来源：

AGRICULTURAL AND BIOLOGICAL CHEMISTRY | 1990年 / 54卷 / 03期

关键词：

D O I：

10.1080/00021369.1990.10870032

中图分类号：

S3 [农学（农艺学）];

学科分类号：

0901 ;

摘要：

A culture similar to Streptomyces variabilis was found to produce a novel cyclic hexadepsipeptide antibiotic named variapeptin. Variapeptin is structurally related to azinothricin, А83586С, and citropeptin. The antibiotic was active against Gram-positive bacteria and showed cytotoxic activity against mammalian cells. © 1990 by the Japan Society for Bioscience, Biotechnology, and Agrochemistry. All rights reserved.

引用

页码：791 / 794

页数：4

共 7 条

[1]

HAYAKAWA Y, IN PRESS AGR BIOL CH

[2] OKILACTOMYCIN, A NOVEL ANTIBIOTIC PRODUCED BY A STREPTOMYCES SPECIES .1. TAXONOMY, FERMENTATION, ISOLATION AND CHARACTERIZATION [J].

IMAI, H ;

SUZUKI, KI ;

MORIOKA, M ;

NUMASAKI, Y ;

KADOTA, S ;

NAGAI, K ;

SATO, T ;

IWANAMI, M ;

SAITO, T .

JOURNAL OF ANTIBIOTICS, 1987, 40 (11) :1475-1482

[3] MICROBIAL PRODUCTS .8. AZINOTHRICIN, A NOVEL HEXADEPSIPEPTIDE ANTIBIOTIC [J].

MAEHR, H ;

LIU, CM ;

PALLERONI, NJ ;

SMALLHEER, J ;

TODARO, L ;

WILLIAMS, TH ;

BLOUNT, JF .

JOURNAL OF ANTIBIOTICS, 1986, 39 (01) :17-25

[4]

NAKAGAWA M, 1989, Patent No. 19079

[5]

SHIRLING E B, 1968, International Journal of Systematic Bacteriology, V18, P69

[6]

SHIRLING E. B., 1966, INT J SYST BACTERIOL, V16, P313

[7] A83586C, A NEW DEPSIPEPTIDE ANTIBIOTIC [J].

SMITKA, TA ;

DEETER, JB ;

HUNT, AH ;

MERTZ, FP ;

ELLIS, RM ;

BOECK, LD ;

YAO, RC .

JOURNAL OF ANTIBIOTICS, 1988, 41 (06) :726-733

← 1 →