STUDY ON THE ENDOTHELIN GENE AND ITS EXPRESSION

被引:7
作者
MASAKI, T [1 ]
YANAGISAWA, M [1 ]
INOUE, A [1 ]
KIMURA, S [1 ]
GOTO, K [1 ]
机构
[1] UNIV TSUKUBA, INST BASIC MED SCI, TSUKUBA, IBARAKI 305, JAPAN
来源
JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION | 1990年 / 54卷 / 09期
关键词
ENDOTHELIN; ISOFORM; GENE; MESSENGER RNA; RECEPTOR;
D O I
10.1253/jcj.54.1221
中图分类号
N09 [自然科学史]; B [哲学、宗教];
学科分类号
01 ; 0101 ; 010108 ; 060207 ; 060305 ; 0712 ;
摘要
Endothelin (ET) is a potent vasoconstrictor peptide produced by vascular endothelial cells. Three distinct human endothelin genes were cloned and analysed. The results demonstrated that there were three distinct mRNAs for ET and that TPA-responsive element, mRNA stabilizing sequence, motifs for binding site of nuclear factor 1 and acute phase reactant regulatory elements were recognized in preproform ET-1 gene.
引用
收藏
页码:1221 / 1225
页数:5
相关论文
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