INTERMITTENT MICROMOTION INHIBITS BONE INGROWTH - TITANIUM IMPLANTS IN RABBITS

被引：130

作者：

ASPENBERG, P ^{[1
]}

GOODMAN, S ^{[1
]}

TOKSVIGLARSEN, S ^{[1
]}

RYD, L ^{[1
]}

ALBREKTSSON, T ^{[1
]}

机构：

[1] INST HANDICAP RES,GOTHENBURG,SWEDEN

来源：

ACTA ORTHOPAEDICA SCANDINAVICA | 1992年 / 63卷 / 02期

基金：

英国医学研究理事会;

关键词：

D O I：

10.3109/17453679209154809

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

We studied the effects of micromotion on bone ingrowth into a 1-mm canal through a titanium chamber implanted in the proximal tibia of rabbits. The implant surface became "osseointegrated," but an interior core was movable, allowing the central portion of the canal to be moved in relation to the ends. Thus, the ingrowing bone in the canal had to pass an area of ad latus motion. When implanted in rabbit tibiae, the canal became filled with ingrown cancellous bone. Bone ingrowth was inhibited by 20 cycles of 0.5-mm movement applied during a 30-second period once daily. With this regimen, the canal was usually filled with vascularized fibrous tissue and significantly less bone. The micromotion chamber may enable detailed studies of the effects of different motion variables on ingrowth of bone.

引用

页码：141 / 145

页数：5

共 18 条

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