ASYMMETRIC HECK REACTION - A CATALYTIC ASYMMETRIC-SYNTHESIS OF THE KEY INTERMEDIATE FOR DELTA-9(12)-CAPNELLENE-3-BETA,8-BETA,10-ALPHA-TRIOL AND DELTA-9(12)-CAPNELLENE-3-BETA,8-BETA,10-ALPHA,14-TETROL

被引：104

作者：

KAGECHIKA, K ^{[1
]}

SHIBASAKI, M ^{[1
]}

机构：

[1] HOKKAIDO UNIV,FAC PHARMACEUT SCI,SAPPORO,HOKKAIDO 060,JAPAN

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1991年 / 56卷 / 13期

关键词：

D O I：

10.1021/jo00013a004

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A catalytic asymmetric synthesis of the key intermediates 21 and 22 for the capnellenols has been achieved (80% ee) by an asymmetric Heck reaction followed by an anion capture process. Furthermore, an improved synthetic route to (+/-)-capnellenols has been also developed.

引用

页码：4093 / 4094

页数：2

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