A FACILE CHIRAL APPROACH TO THE DENDROBINE SKELETON BY INTRAMOLECULAR PAUSON-KHAND REACTION

被引：45

作者：

TAKANO, S

INOMATA, K

OGASAWARA, K

机构：

来源：

CHEMISTRY LETTERS | 1992年 / 03期

关键词：

D O I：

10.1246/cl.1992.443

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A possible chiral synthetic route to the alkaloid (-)-dendrobine has been explored by employing intramolecular Pauson-Khand reaction as the key step. The cobalt complex generated from (S)-carvone yielded a single stereoisomer (10) on intramolecular Pauson-Khand reaction. The adduct 10 was transformed into decarboxy-7,9-dihydrodendrobine by a four-step reaction.

引用

页码：443 / 446

页数：4

共 25 条

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