SYNTHESIS, SPECTRAL STUDIES AND TRITIATION OF THE CANNABINOID ANTAGONIST SR141716A

被引：35

作者：

SELTZMAN, HH

CARROLL, FI

BURGESS, JP

WYRICK, CD

BURCH, DF

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1995年 / 15期

关键词：

D O I：

10.1039/c39950001549

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient synthesis of the cannabinoid antagonist SR141716A is presented and the structure is established by nOe experiments; tritiated SR141716A is synthesized by a novel sequence of metallation-iodination-tritiation and the labelled site is shown by tritium NMR and tritium-hydrogen nOe experiments.

引用

页码：1549 / 1550

页数：2

共 15 条

[1] A REGIOSELECTIVE ROUTE TO 3-ALKYL-1-ARYL-1H-PYRAZOLE-5-CARBOXYLATES - SYNTHETIC STUDIES AND STRUCTURAL ASSIGNMENTS [J].