STRUCTURAL STUDIES OF THE CAPSULAR ANTIGEN FROM STREPTOCOCCUS-PNEUMONIAE TYPE-26

被引:54
作者
KENNE, L
LINDBERG, B
MADDEN, JK
机构
[1] Department of Organic Chemistry, Arrhenius Laboratory, University of Stockholm
关键词
D O I
10.1016/S0008-6215(00)85487-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The structure of the capsular antigen from Pneumococcus type 26 has been determined by using methylation analysis, periodate-oxidation studies, and n.m.r. spectroscopy of the original and the dephosphorylated product. It is concluded that the polysaccharide is composed of repeating-units having the following structure. {A figure is presented} The only difference between this structure and that of the type-6 antigen is that the α-l-rhamnopyranosyl residue is linked to O-4 of d-ribitol in the former, but to O-3 in the latter. © 1979.
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页码:175 / 182
页数:8
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