EFFICIENT REDUCTION OF AZIDES TO AMINES WITH TRIBUTYLSTANNANE - HIGH-YIELD SYNTHESES OF AMINO AND DIAMINO DEOXYNUCLEOSIDES

被引：49

作者：

SAMANO, MC ^{[1
]}

ROBINS, MJ ^{[1
]}

机构：

[1] BRIGHAM YOUNG UNIV,DEPT CHEM,PROVO,UT 84602

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 44期

关键词：

D O I：

10.1016/0040-4039(91)80150-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of unprotected azido-deoxynucleosides with tributylstannane/AIBN in hot benzene/DMAC (or silyl-protected derivatives in benzene) resulted in formation of the corresponding amino-deoxynucleosides in high isolated yields. A radical process is indicated.

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页码：6293 / 6296

页数：4

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