NOVEL SPONGE-DERIVED AMINO-ACIDS .14. NEW STRUCTURES AND BIOACTIVITY PATTERNS OF BENGAZOLE ALKALOIDS FROM A CHORISTID MARINE SPONGE

被引：71

作者：

RODRIGUEZ, J

NIETO, RM

CREWS, P

机构：

[1] UNIV CALIF SANTA CRUZ,DEPT CHEM & BIOCHEM,SANTA CRUZ,CA 95064

[2] UNIV CALIF SANTA CRUZ,INST MARINE SCI,SANTA CRUZ,CA 95064

来源：

JOURNAL OF NATURAL PRODUCTS | 1993年 / 56卷 / 12期

关键词：

D O I：

10.1021/np50102a002

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

New bengazoles 3-9 as inseparable mixtures are reported from the sponge Jaspis cf. coricea collected in Papua New Guinea, These compounds contain a new variation of the unusual bisoxazole core present in bengazole A [1]. The B-ring oxazole hexatetraol side chain is varyingly substituted with either myristic acid or 13-methylmyristic acid. Hydrolysis of three different bengazole mixtures each yielded an identical tetraol, bengazole Z [11].

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页码：2034 / 2040

页数：7

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