A NEW METHOD FOR THE DETRITYLATION OF ALCOHOLS BEARING OTHER REDUCIBLE AND ACID-HYDROLYZABLE FUNCTIONALITIES

被引：14

作者：

KRAINER, E ^{[1
]}

NAIDER, F ^{[1
]}

BECKER, J ^{[1
]}

机构：

[1] UNIV TENNESSEE,DEPT MICROBIOL,KNOXVILLE,TN 37996

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 11期

关键词：

D O I：

10.1016/S0040-4039(00)60759-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Instantaneous cleavage of a trityl ether was achieved using a non-reductive acidolytic procedure. Treatment of protected azidouridine 1 with a mixture of TFA/ TFAA in CH2Cl2 resulted in quantitative detritylation as judged by TLC. The OH-5' group was liberated by addition of Et3N and quenching with MeOH. No significant cleavage of the acid hydrolyzable SEM [beta-(trimethylsilyl) ethoxymethyl] protecting groups was detected.

引用

页码：1713 / 1716

页数：4

共 18 条

[1] 9-PHENYLXANTHEN-9-YL PROTECTING GROUP [J].