AN UNUSUALLY SMALL POTASSIUM CURRENT THAT IS WELL-SUITED TO A RETINAL NEURON WHICH IS CHRONICALLY DEPOLARIZED

被引:8
作者
SULLIVAN, JM [1 ]
LASATER, EM [1 ]
机构
[1] UNIV UTAH,SCH MED,DEPT OPHTHALMOL,SALT LAKE CITY,UT 84108
关键词
Horizontal cell; Patch clamp; Potassium current; Retina;
D O I
10.1016/0006-8993(90)90204-O
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Here we describe a sustained outward potassium current (IK) in retinal horizontal cells (HCs). IK is unusually small over the range of membrane potentials normally experienced by these cells, which are chronically depolarized. We hypothesize that this unique IK will reduce the amount of neurotransmitter required to shift the cell's membrane potential over a wide range, and will minimize the redistribution of potassium ions across the post-synaptic memebrane when the cell is depolarized. © 1990.
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页码:130 / 132
页数:3
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