ELIMINATION OF GD-DTPA BY MEANS OF HEMODIALYSIS

被引：15

作者：

HAUSTEIN, J

SCHUHMANNGIAMPIERI, G

机构：

[1] Department of Clinical Research Diagnostics, Schering AG Berlin

[2] Department of Preclinical Research Diagnostics, Schering AG Berlin

来源：

EUROPEAN JOURNAL OF RADIOLOGY | 1990年 / 11卷 / 03期

关键词：

Contrast medium; Gadolinium; MR; renal failure; hemodialysis; Magnetic resonance; contrast medium; Gd-DTPA; Renal failure;

D O I：

10.1016/0720-048X(90)90064-I

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

After intravenous administration of Gd-DTPA (0.1 mmol/kg) hemodialysis was performed five times within 6 days in a patient with endstage renal failure. During the fifth hemodialysis a blood sample of 5 ml was withdrawn and Gd-concentration was measured in plasma at 342.247 nm using the method of Inductively Coupled Plasma Atomic Emission Spectrometry. Gd-concentration measured in venous and arterial blood was 6 × 10-6 mol/liter, corresponding to 1.5% of the dose administered. If these data can be confirmed in more patients with endstage renal failure, this is the proof of effective hemodialysis of Gd-DTPA in a clinical setting. © 1990.

引用

页码：227 / 229

页数：3

共 14 条

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