COMPARATIVE-STUDY OF PINEAL ACETYL-COA HYDROLASE AND N-ACETYLTRANSFERASE ACTIVITIES

被引:6
作者
NAMBOODIRI, MAA [1 ]
NAMBOODIRI, MA [1 ]
WELLER, JL [1 ]
KLEIN, DC [1 ]
机构
[1] NICHHD,NEUROENDOCRINOL SECT,DEV NEUROBIOL LAB,BLDG 6,ROOM 128,BETHESDA,MD 20014
关键词
D O I
10.1111/j.1471-4159.1979.tb04506.x
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
pineal acetyl‐CoA hydrolase is measurable at 4 days before birth. It increases rapidly to a maximum of 0.37 nmol/min/0.1 mg protein during the first week after birth, thereafter gradually decreasing and stabilizing at adult levels (0.27 nmol/min/0.1 mg protein) 3‐4 weeks after birth. Unlike A/‐acetyltransferase, the activity of acetyl‐CoA hydrolase does not increase following treatment with isoproterenol, does not exhibit a circadian rhythm and is not inactivated on exposure of the animals to light at night. In addition, denervation of the pineal gland does not alter acetyl‐CoA hydrolase activity. Copyright © 1979, Wiley Blackwell. All rights reserved
引用
收藏
页码:31 / 33
页数:3
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