MORPHOLOGIC, BIOCHEMICAL AND PHYSIOLOGIC ALTERATIONS IN A CASE OF IDIOPATHIC HYPOALBUMINEMIA [ANALBUMINEMIA)

被引：26

作者：

WEINSTOCK, JV ^{[1
]}

KAWANISHI, H ^{[1
]}

SISSON, J ^{[1
]}

机构：

[1] UNIV MICHIGAN, MED CTR, DEPT INTERNAL MED, DIV GASTROENTEROL, ANN ARBOR, MI 48109 USA

来源：

AMERICAN JOURNAL OF MEDICINE | 1979年 / 67卷 / 01期

关键词：

D O I：

10.1016/0002-9343(79)90089-5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A patient with idiopathic hypoalbuminemia is described. A study of albumin kinetics demonstrated slowed albumin degradation suggesting low albumin synthesis. Morphologic observation of hepatocellular alterations suggested decreased protein synthesis. The intra- and extravascular space was low with an abnormally large postural shift of intravascular fluid into the extravascular compartment. Disturbances in the concentration of plasma lipids and of several plasma proteins were detected. The effect of albumin infusion on these physiologic and biochemical abnormalities suggests that most occurred as a secondary response to the hypoalbuminemic state. Evaluation of the patient's kindred revealed no members with hypoalbuminemia. © 1979.

引用

页码：132 / 139

页数：8

共 37 条

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