ISCHEMIC-HEART-DISEASE RISK IN POSTMENOPAUSAL WOMEN - EFFECTS OF ESTROGEN USE ON GLUCOSE AND INSULIN LEVELS

被引：151

作者：

BARRETTCONNOR, E

LAAKSO, M

机构：

[1] Dept. of Comm. and Family Medicine, University of California, San Diego, San Diego, CA

[2] University of California, San Diego, San Diego, CA

[3] Department of Medicine, Kuopio University, Central Hospital, Kuopio

[4] Dept. of Comm. and Family Medicine, University of California, San Diego, San Diego

来源：

ARTERIOSCLEROSIS | 1990年 / 10卷 / 04期

关键词：

Estrogen; Glucose; Insulin; Menopause;

D O I：

10.1161/01.ATV.10.4.531

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report the fasting and post-challenge plasma insulin and glucose levels in 469 nondiabetic postmenopausal women from the Rancho Bernardo cohort according to the current use of estrogen replacement therapy. In these older women, the use of noncontraceptive estrogen was not associated with impaired glucose tolerance. Estrogen-treated women had lower levels of insulin than women who were not taking estrogen; these differences were not explained by age, obesity, or differential hormone use by women with known glucose intolerance. There were no significant differences in glucose and insulin levels in those taking conjugated equine estrogen (Premarin) alone compared to those taking it with medroxyprogesterone acetate (Provera).

引用

页码：531 / 534

页数：4

共 23 条

[1] ROLE OF OVARIAN HORMONES IN THE LONG-TERM CONTROL OF GLUCOSE-HOMEOSTASIS - EFFECTS ON INSULIN-SECRETION [J].