FRUCTOSE 2,6-BISPHOSPHATE AND 6-PHOSPHOFRUCTO-2-KINASE DURING LIVER-REGENERATION

被引：21

作者：

ROSA, JL ^{[1
]}

VENTURA, F ^{[1
]}

CARRERAS, J ^{[1
]}

BARTRONS, R ^{[1
]}

机构：

[1] UNIV BARCELONA,FAC ODONTOL,DEPT CIENCIES FISIOLOG HUMANES & NUTR,UNITAT BIOQUIM,E-08907 LHOSP,SPAIN

来源：

BIOCHEMICAL JOURNAL | 1990年 / 270卷 / 03期

关键词：

D O I：

10.1042/bj2700645

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Glycogen and fructose 2,6-bisphosphate levels in rat liver decreased quickly after partial hepatectomy. After 7 days the glycogen level was normalized and fructose 2,6-bisphosphate concentration still remained low. The 'active' (non-phosphorylated) form of 6-phosphofructo-2-kinase varied in parallel with fructose 2,6-bisphosphate levels, whereas the 'total' activity of the enzyme decreased only after 24 h, similarly to glucokinase. The response of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase from hepatectomized rats (96 h) to sn-glycerol 3-phosphate and to cyclic AMP-dependent protein kinase was different from that of the enzyme from control animals and similar to that of the foetal isoenzyme.

引用

页码：645 / 649

页数：5

共 40 条

[1] HORMONAL-CONTROL OF FRUCTOSE 2,6-BISPHOSPHATE CONCENTRATION IN ISOLATED RAT HEPATOCYTES [J].