MRI IN PRIMARY BONE-TUMORS - THERAPEUTIC IMPLICATIONS

被引:18
作者
GOLFIERI, R
BADDELEY, H
PRINGLE, JS
LEUNG, AWL
GRECO, A
SOUHAMI, R
机构
[1] The Paul Strickland Scanner Centre, Mount Vernon Hospital, Northwood
[2] The London Bone Tumour Service, The Institute of Orthopaedic's., London
关键词
BONE NEOPLASM; MRI; STAGING; MAGNETIC RESONANCE IMAGING; COMPARATIVE STUDY;
D O I
10.1016/0720-048X(91)90073-5
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
The accuracy of preoperative MRI in detecting tumor extent has been evaluated in 35 patients with primary bone neoplasms; intra-osseous extent was measured on MR images and compared with macroslides of surgical specimens in 26 cases. An almost completely accurate prediction of tumor size was obtained with the combined employment of Spin-Echo (SE) and Short Inversion Time Inversion Recovery (STIR) sequences in the various tumors, with the exception of two Ewing's sarcomas. Changes in Signal Intensity (SI) and tumor morphology were identified in those cases which had undergone presurgical chemotherapy: the reduction in SI and in tumor size or the appearance of a more homogeneous signal was correlated with a positive response to cytotoxic therapy. MR imaging fully satisfies surgeon's preoperative requirements in the assessment of therapy-responding neoplasms as well as in local tumor staging in all types of neoplasms, with the exception of Ewing's sarcoma.
引用
收藏
页码:201 / 207
页数:7
相关论文
共 29 条
  • [1] Aisen, Martel, Braunstein, McMillin, Phillips, Kling, MRI and CT evaluation of primary bone and soft tissue tumors, AJR, 146, pp. 749-756, (1986)
  • [2] Berquist, Bone and soft tissue tumors, Magnetic Resonance of the Musculoskeletal System, pp. 85-108, (1987)
  • [3] Bloem, Bluemm, Taminiau, Van Oosterom, Stolk, Doornbos, Magnetic resonance imaging of primary malignant bone tumors, Radiographics, 7, pp. 425-445, (1987)
  • [4] Bloem, Taminiau, Eulderink, Hermans, Pauwels, Radiologic staging of primary bone sarcoma. MR imaging, scintigraphy, angiography and CT correlated with pathologic examination, Radiology, 169, pp. 805-810, (1988)
  • [5] Boyko, Cory, Cohen, Provisor, Mirkin, DeRosa, MR imaging of osteogenic and Ewing's sarcoma, AJR, 148, pp. 317-322, (1987)
  • [6] Bydder, Young, MR imaging: clinical use of Inversion Recovery sequence, J Comput Assist Tomogr, 9, pp. 659-675, (1985)
  • [7] Bydder, Steiner, Blumgart, Khenia, Young, MR of the liver using short TI Inversion Recovery Sequences, J Comput Assist Tomogr, 9, pp. 1084-1089, (1985)
  • [8] Burk, Dalinka, Schiebler, Cohen, Kressel, Strategies for musculoskeletal magnetic resonance imaging, Rad Clin North Am, 26, pp. 653-672, (1988)
  • [9] Campanacci, Surgical treatment: margins and reconstructions, Presented at the Consensus meeting on Osteosarcoma: state of art in Europe, (1987)
  • [10] Chawla, Benjamin, Jaffe, Et al., Preoperative intra-arterial cisplatin and limb salvage surgery for patients with high-grade osteosarcoma of the extremities, Adjuvant therapy of cancer, 5, pp. 701-710, (1987)