Localization of the Gene Encoding Human Factor V to Chromosome 1q21-25

被引：34

作者：

Wang, H. ^{[1
]}

Riddell, D. C. ^{[1
]}

Guinto, E. R. ^{[2
]}

MacGillivray, R. T. A. ^{[2
]}

Hamerton, J. L. ^{[1
]}

机构：

[1] Univ Manitoba, Dept Human Genet, Winnipeg, MB R3E 0W3, Canada

[2] Univ British Columbia, Dept Biochem, Vancouver, BC V6T 1W5, Canada

来源：

GENOMICS | 1988年 / 2卷 / 04期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/0888-7543(88)90021-3

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The gene encoding human coagulation Factor V (FV), one of the cofactors in the blood clotting process, has been mapped to chromosome 1 by both Southern hybridization to DNA from human-hamster somatic cell hybrids and in situ hybridization. The whole plasmid pUC3A containing a 1.5-kb cDNA sequence for FV was P-32-labeled for Southern analysis and H-3-labeled for in situ hybridization to metaphase chromosomes. The results localized the FV gene to the region of 1q21-25. (C) 1988 Academic Press, Inc.

引用

页码：324 / 328

页数：5

共 21 条

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