ISOLATION AND STRUCTURE DETERMINATION OF A NEW MARINE NEUROTOXIN FROM THE NEW-ZEALAND SHELLFISH, AUSTROVENUS-STUTCHBURYI

被引:9
作者
ISHIDA, H [1 ]
NOZAWA, A [1 ]
NUKAYA, H [1 ]
TSUJI, K [1 ]
KASPAR, H [1 ]
BERKETT, N [1 ]
KOSUGE, T [1 ]
机构
[1] CAWTHRON INST, NELSON, NEW ZEALAND
关键词
D O I
10.1016/0041-0101(94)90326-3
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
A new marine neurotoxin was isolated from a water extract of the New Zealand shellfish, Austrovenus stutchburyi, by chromatography on columns of Sephadex G-15 and LH-20, followed by reverse-phase HPLC. It was identified as (4-methoxycarbonylbutyl)trimethyl-ammonium chloride, and this was confirmed by synthesis.
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页码:1672 / 1674
页数:3
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