HEART-TRANSPLANTATION FOR CHAGAS CARDIOMYOPATHY

被引:21
作者
BLANCHE, C
ALEKSIC, I
TAKKENBERG, JJM
CZER, LSC
FISHBEIN, MC
TRENTO, A
机构
[1] Department of Cardiothoracic Surgery, Cedars-Sinai Medical Center, Los Angeles, CA
关键词
D O I
10.1016/0003-4975(95)00726-2
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We present 2 patients who underwent orthotopic heart transplantation for end-stage Chagas' cardiomyopathy. Despite immunosuppressive therapy, postoperative prophylaxis with nifurtimox appeared to prevent Trypanosoma cruzi reactivation. Neither patient has shown signs of Chagas' myocarditis, and both are clinically well 12 and 72 months after transplantation. The successful outcome of our patients suggests that heart transplantation is a reasonable therapeutic option in patients with endstage Chagas' cardiomyopathy.
引用
收藏
页码:1406 / 1409
页数:4
相关论文
共 12 条
  • [1] BLANCO OAL, 1992, TRANSPL P, V24, P3089
  • [2] BOCCHI EA, 1993, TRANSPLANT P, V25, P1329
  • [3] BOCCHI EA, 1994, CIRCULATION, V90, P153
  • [4] CHAGAS HEART-DISEASE IN THE UNITED-STATES
    HAGAR, JM
    RAHIMTOOLA, SH
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1991, 325 (11) : 763 - 768
  • [5] KIRCHHOFF LV, 1993, INFECT DIS CLIN N AM, V7, P487
  • [6] KIRCHHOFF LV, 1993, NEW ENGL J MED, V329, P639, DOI 10.1056/NEJM199308263290909
  • [7] LIBOW LF, 1991, CUTIS, V48, P37
  • [8] LUDERS C, 1992, TRANSPL P, V24, P1878
  • [9] DOES CHAGAS-DISEASE EXIST AS AN UNDIAGNOSED FORM OF CARDIOMYOPATHY IN THE UNITED-STATES
    MILEI, J
    MAUTNER, B
    STORINO, R
    SANCHEZ, JA
    FERRANS, VJ
    [J]. AMERICAN HEART JOURNAL, 1992, 123 (06) : 1732 - 1735
  • [10] MOREIRA LFP, 1991, CIRCULATION, V84, P296