GLYCOPROTEIN HORMONE ALPHA-SUBUNIT IN PITUITARY-ADENOMAS

被引：61

作者：

BECKPECCOZ, P

PERSANI, L

FAGLIA, G

机构：

来源：

TRENDS IN ENDOCRINOLOGY AND METABOLISM | 1992年 / 3卷 / 02期

关键词：

D O I：

10.1016/1043-2760(92)90041-X

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Elevated serum glycoprotein hormone alpha-subunit (alpha-subunit) levels are seen in about one of six patients bearing pituitary adenomas. This finding has particular clinical significance in patients with nonfunctioning pituitary adenomas. Moreover, the measurement of alpha-subunit along with the calculation of the molar ratio between alpha-subunit and TSH, LH, or FSH is helpful in the diagnosis of glycoprotein hormone-secreting pituitary adenomas. Since serum alpha-subunit levels may vary greatly in several physiologic and pathologic conditions, care has to be taken to differentiate abnormal from normal states of alpha-subunit hypersecretion as well as to exclude causes of alpha-subunit overproduction only casually associated with the presence of pituitary tumors.

引用

页码：41 / 45

页数：5

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