ALLOGENEIC MARROW TRANSPLANTATION FOR ACUTE-LEUKEMIA IN RELAPSE

被引：68

作者：

BADGER, C ^{[1
]}

BUCKNER, CD ^{[1
]}

THOMAS, ED ^{[1
]}

CLIFT, RA ^{[1
]}

SANDERS, JE ^{[1
]}

STEWART, PS ^{[1
]}

STORB, R ^{[1
]}

SULLIVAN, KM ^{[1
]}

SHULMAN, H ^{[1
]}

FLOURNOY, N ^{[1
]}

机构：

[1] UNIV WASHINGTON, SCH MED, SEATTLE, WA 98195 USA

来源：

LEUKEMIA RESEARCH | 1982年 / 6卷 / 03期

关键词：

D O I：

10.1016/0145-2126(82)90101-1

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The results of allogeneic marrow transplantation in 75 patients with acute lymphoblastic leukemia and 63 patients with acute non-lymphoblastic leukemia in relapse are reviewed. The effects of various chemotherapeutic regimens added to the basic regimen of cyclophosphamide (Cy) 60 mg/kg given on each of 2 successive days followed by 1000 rad of total body irradiation (TBI) were evaluated. The regimens tested were dimethylbusulphan (DMB), 1,3-(bis(2-chlorethyl)-1-nitrosourea (BCNU) and daunorubicin. Seventeen of 138 patients are alive between 3 and 9.5 yr from transplantation. The addition of other chemotherapeutic agents to the basic Cy and TBI regimen did not decrease relapse frequency or prolong survival.

引用

页码：383 / 387

页数：5

共 17 条

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