NEW INHALATION ANESTHETICS .5. FLUORINATED BUTANES (AND BUTENES)

被引:6
作者
BAGNALL, RD [1 ]
BELL, W [1 ]
PEARSON, K [1 ]
机构
[1] ICI LTD,DIV PHARMACEUT,MACCLESFIELD SK10 4TG,CHESHIRE,ENGLAND
关键词
D O I
10.1016/S0022-1139(00)82082-5
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
A range of fluorohalobutanes has been prepared for screening as potential inhalation anaesthetics by chlorination and fluorination of halogenated butanes and butenes. Surprisingly, several fluorohalobutenes were obtained as side products of the fluorination of halogenated butanes, and there was evidence of considerable rearrangement of the butane carbon skeleton, None of the compounds tested, however, gave good anaesthesia with no side effects. © 1979.
引用
收藏
页码:325 / 335
页数:11
相关论文
共 5 条
[1]   NEW INHALATION ANESTHETICS .1. FLUORINATED 1,3-DIOXOLANE DERIVATIVES [J].
BAGNALL, RD ;
BELL, W ;
PEARSON, K .
JOURNAL OF FLUORINE CHEMISTRY, 1977, 9 (05) :359-375
[2]  
BAGNALL RD, 1978, J FLUORINE CHEM, V11, P93, DOI 10.1016/S0022-1139(00)81010-6
[3]   NEW INHALATION ANESTHETICS .3. FLUORINATED ALIPHATIC ETHERS [J].
BAGNALL, RD ;
BELL, W ;
PEARSON, K ;
JEATER, A .
JOURNAL OF FLUORINE CHEMISTRY, 1979, 13 (02) :123-140
[4]   NEW INHALATION ANESTHETICS .4. FLUORINATED PROPANES [J].
BAGNALL, RD ;
BELL, W ;
PEARSON, K .
JOURNAL OF FLUORINE CHEMISTRY, 1979, 13 (03) :209-223
[5]  
GLEN JJ, UNPUBLISHED