A SIMPLE PHOTOKINETIC METHOD FOR THE DETERMINATION OF NITROPRUSSIDE IN BIOLOGICAL AND PHARMACEUTICAL SAMPLES

被引：5

作者：

PEREZRUIZ, T

MARTINEZLOZANO, MC

TOMAS, V

LOPEZBALSERA, C

机构：

[1] Department of Analytical Chemistry, Faculty of Sciences, University of Murcia, Murcia

来源：

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 1991年 / 9卷 / 02期

关键词：

NITROPRUSSIDE; INHIBITION; PHOTOKINETIC METHOD;

D O I：

10.1016/0731-7085(91)80135-V

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A simple method has been developed for the determination of nitroprusside in human serum and pharmaceutical preparations. The new method is based on the strong inhibitory effect of nitroprusside on the photochemical reduction of phloxin by ethylenediaminetetra-acetic acid. The rate measurements are accomplished very simply by measuring the time needed for the absorbance to be reduced to 1/10 of its initial value. Optimal conditions for the determination of nitroprusside at concentrations of 15-200 ng ml-1 are described.

引用

页码：123 / 128

页数：6

共 28 条

[1] POLAROGRAPHIC-DETERMINATION OF NITROPRUSSIDE IN HUMAN-SERUM [J].