GAMMA-INTERFERON AND INTERLEUKIN-2, BUT NOT INTERLEUKIN-4, ARE DETECTABLE IN GAMMA-DELTA T-CELL CULTURES AFTER ACTIVATION WITH BACTERIA

被引：91

作者：

FOLLOWS, GA ^{[1
]}

MUNK, ME ^{[1
]}

GATRILL, AJ ^{[1
]}

CONRADT, P ^{[1
]}

KAUFMANN, SHE ^{[1
]}

机构：

[1] UNIV ULM, DEPT IMMUNOL, ALBERT EINSTEIN ALLEE 11, W-7900 ULM, GERMANY

来源：

INFECTION AND IMMUNITY | 1992年 / 60卷 / 03期

关键词：

D O I：

10.1128/IAI.60.3.1229-1231.1992

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Mycobacterium tuberculosis- or group A streptococcus-activated gamma/delta T cells from normal healthy individuals were negatively sorted and restimulated in vitro for 48 h. Significant amounts of gamma interferon were detected after restimulation with M. tuberculosis, group A streptococci, or Listeria monocytogenes. In contrast, interleukin 4 was undetectable in the culture supernatants. Our findings provide indirect evidence for the involvement of gamma/delta-T cells in immunity against tubercle bacilli and probably other bacteria.

引用

页码：1229 / 1231

页数：3

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