ANAPHYLACTIC ANESTHETIC REACTIONS - THE VALUE OF PAPER RADIOALLERGOSORBENT TESTS FOR IGE ANTIBODIES TO MUSCLE-RELAXANTS AND THIOPENTONE

被引:35
作者
ASSEM, ESK [1 ]
机构
[1] UNIV COLL HOSP LONDON,WC1 LONDON,ENGLAND
关键词
Allergy; anaphylaxis; thiopentone; Neuromuscular relaxants; suxamethonium; alcuronium;
D O I
10.1111/j.1365-2044.1990.tb14881.x
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
The three currently available paper radioallergosorbent tests (‘suxamethonium’, alcuronium and thiopentone) were evaluated. ‘Suxamethonium’ radioallergosorbent test (which employs choline conjugated to paper discs) proved to be reliable in the detection of allergy to neuromuscular blockers, which were confirmed as the most common cause of anaphylactic reaction during general anaesthesia. Thiopentone radioallergosorbent test may also be useful, and is recommended in conjunction with ‘suxamethonium’ radioallergosorbent test in the preliminary investigation of reactions. Patients with positive ‘suxamethonium’ radioallergosorbent test usually require further testing, including alcuronium radioallergosorbent test, skin testing with a wide range of drug concentrations or leucocyte histamine release test. Copyright © 1990, Wiley Blackwell. All rights reserved
引用
收藏
页码:1032 / 1038
页数:7
相关论文
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