A PILOT-STUDY OF A NEUROENDOCRINE TEST BATTERY IN POSTTRAUMATIC-STRESS-DISORDER

被引：35

作者：

DINAN, TG ^{[1
]}

BARRY, S ^{[1
]}

YATHAM, LN ^{[1
]}

MOBAYED, M ^{[1
]}

BROWN, I ^{[1
]}

机构：

[1] NATL UNIV IRELAND UNIV COLL DUBLIN,DEPT PSYCHIAT,DUBLIN 4,IRELAND

来源：

BIOLOGICAL PSYCHIATRY | 1990年 / 28卷 / 08期

关键词：

D O I：

10.1016/0006-3223(90)90453-9

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Eight female patients who fulfilled DSM-III criteria for posttraumatic stress disorder (PTSD) took part in this study. They were each assessed using the dexamethasone suppression test, the desipramine/growth hormone stimulation test, which examines alpha-2-adrenoceptor functioning, and the buspirone/prolactin test, which is thought to examine 5-HT receptor functioning. A control group consisting of age- and sex-matched healthy subjects was also tested. For each subject the three tests were conducted over 5 days. Hormone assays were carried out blind to diagnosis. Overall no differences on any of the three tests were detected between the patients and controls. The results do not support a link between PTSD and major depression. © 1990.

引用

页码：665 / 672

页数：8

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