PRESENCE OF LEISHMANIA-BRAZILIENSIS IN BLOOD-SAMPLES FROM CURED PATIENTS OR AT DIFFERENT STAGES OF IMMUNOTHERAPY

被引：32

作者：

GUEVARA, P

ROJAS, E

GONZALEZ, N

SCORZA, JV

ANEZ, N

VALERA, M

RAMIREZ, JL

机构：

[1] CENT UNIV VENEZUELA,FAC CIENCIAS,MOLEC GENET GRP,CARACAS 10141A,VENEZUELA

[2] UNIV LOS ANDES,CTR TRUJILLANO INVEST JOSE W TORREALBA,TRUJILLO,VENEZUELA

[3] UNIV LOS ANDES,FAC CIENCIAS,MERIDA 5101,VENEZUELA

来源：

CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY | 1994年 / 1卷 / 04期

关键词：

D O I：

10.1128/CDLI.1.4.385-389.1994

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

By using a PCR assay specific far Leishmania braziliensis in blood samples, we detected this parasite in patients cured by immunotherapy or at different stages of treatment. We also found the parasite in subjects who had never suffered leishmaniasis but who had lived in endemic areas and migrated to nonendemic ones many years ago. These results suggest that L. braziliensis infections are difficult to eradicate and that a clinical cure but rarely a complete elimination of the parasite is generally accomplished.

引用

页码：385 / 389

页数：5

共 17 条

[1] PERSISTENCE OF VIRULENT LEISHMANIA-MAJOR IN MURINE CUTANEOUS LEISHMANIASIS - A POSSIBLE HAZARD FOR THE HOST [J].

AEBISCHER, T ;

MOODY, SF ;

HANDMAN, E .

INFECTION AND IMMUNITY, 1993, 61 (01) :220-226

[2]

ANEZ N, 1988, Memorias do Instituto Oswaldo Cruz, V83, P455, DOI 10.1590/S0074-02761988000400011

[3]

BASTUJIGARIN S, 1991, ANN DERMATOL VENER, V118, P860

[4]

CONVIT J, 1987, LANCET, V1, P401

[5] IS LEISHMANIASIS EVER CURED [J].

DEROSSELL, RA ;

DEDURAN, RD ;

ROSSELL, O ;

RODRIGUEZ, AM .

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1992, 86 (03) :251-253

[6] PERIPHERAL INTRAMONOCYTIC LEISHMANIAS IN AN AIDS PATIENT [J].

FILLOLA, G ;

CORBERAND, JX ;

LAHARRAGUE, PF ;

LEVENES, H ;

MASSIP, P ;

RECCO, P .

JOURNAL OF CLINICAL MICROBIOLOGY, 1992, 30 (12) :3284-3285

[7]

GALINDO I, 1993, APPL MICROBIOL BIOT, V39, P553, DOI 10.1007/BF00205050

[8]

Greenblatt C L, 1980, Prog Clin Biol Res, V47, P259

[9] IDENTIFICATION OF NEW-WORLD LEISHMANIA USING RIBOSOMAL GENE SPACER PROBES [J].

GUEVARA, P ;

ALONSO, G ;

DASILVEIRA, JF ;

DEMELLO, M ;

SCORZA, JV ;

ANEZ, N ;

RAMIREZ, JL .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1992, 56 (01) :15-26

[10] LEISHMANIA-BRAZILIENSIS IN BLOOD 30 YEARS AFTER CURE [J].

GUEVARA, P ;

RAMIREZ, JL ;

ROJAS, E ;

SCORZA, JV ;

GONZALEZ, N ;

ANEZ, N .

LANCET, 1993, 341 (8856) :1341-1341

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