EFFECT OF 2,4-DINITROPHENOL ON PROPERTIES OF THIN PHOSPHOLIPID FILMS

The properties of a system consisting of a thin phospholipid film separating two electrolyte solutions containing 1 mm 2,4-dinitrophenol have been studied. Both the variation of electrical conductance as a function of pH, keeping the pH the same on both sides of the membrane, and the nonlinear variation of electrical potential difference as a function of pH difference across the membrane have been explained in terms of lipid-soluble complexes of the type XP2- where X is a cation and P dinitrophenate. The maximum conductance was found to be 1.4×10-5 mhos cm-2 at pH 4.2. © 1969 Springer-Verlag New York Inc.