HAS SCLEROTHERAPY ALTERED THE MANAGEMENT OF PATIENTS WITH VARICEAL BLEEDING

被引:28
作者
TERBLANCHE, J [1 ]
机构
[1] UNIV CAPE TOWN,SCH MED,MRC,LIVER RES CTR,CAPE TOWN 7925,SOUTH AFRICA
关键词
D O I
10.1016/S0002-9610(05)80866-9
中图分类号
R61 [外科手术学];
学科分类号
摘要
Sclerotherapy is currently the primary treatment of choice for the majority of patients who present with esophageal variceal bleeding. Although it has altered the management of these patients, unanswered questions and controversies remain. Patients with acute variceal bleeding should preferably be treated in a specialized center. The primary treatment should be immediate sclerotherapy, when possible. Portosystemic shunts and esophageal transection should be reserved for the 5% to 10% of patients in whom sclerotherapy fails to control acute bleeding. There are several treatment options for long-term management after a variceal bleeding episode. Sclerotherapy is one option and has become the primary treatment in most major centers. All patients with end-stage liver disease must be considered for liver transplantation, and sclerotherapy should be the primary method of treatment in those who are selected. Pharmacologic therapy remains controversial. I propose that portosystemic shunts and devascularization and transection operations be reserved for those few patients in whom sclerotherapy fails to eradicate the varices and to prevent recurrent variceal bleeding. Patients in whom sclerotherapy is unsuccessful should be identified and treated early. © 1990 Reed Publishing USA.
引用
收藏
页码:37 / 42
页数:6
相关论文
共 46 条
  • [1] Atamkuri S P, 1988, Indian J Gastroenterol, V7, P87
  • [2] BARSOUM MS, 1982, BRIT J SURG, V69, P76, DOI 10.1002/bjs.1800690206
  • [3] PREDICTION OF VARICEAL HEMORRHAGE BY ESOPHAGEAL ENDOSCOPY
    BEPPU, K
    INOKUCHI, K
    KOYANAGI, N
    NAKAYAMA, S
    SAKATA, H
    KITANO, S
    KOBAYASHI, M
    [J]. GASTROINTESTINAL ENDOSCOPY, 1981, 27 (04) : 213 - 218
  • [4] RIGID VERSUS FIBEROPTIC ENDOSCOPIC INJECTION SCLEROTHERAPY - A PROSPECTIVE RANDOMIZED CONTROLLED TRIAL IN PATIENTS WITH BLEEDING ESOPHAGEAL-VARICES
    BORNMAN, PC
    KAHN, D
    TERBLANCHE, J
    WORTHLEY, C
    SPENCE, RAJ
    KRIGE, JJEJ
    [J]. ANNALS OF SURGERY, 1988, 208 (02) : 175 - 178
  • [5] BORNMAN PC, 1986, S AFR MED J, V70, P34
  • [6] A COMPARISON OF SCLEROTHERAPY WITH STAPLE TRANSECTION OF THE ESOPHAGUS FOR THE EMERGENCY CONTROL OF BLEEDING FROM ESOPHAGEAL-VARICES
    BURROUGHS, AK
    HAMILTON, G
    PHILLIPS, A
    MEZZANOTTE, G
    MCINTYRE, N
    HOBBS, KEF
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1989, 321 (13) : 857 - 862
  • [7] ENDOSCOPIC SCLEROTHERAPY VERSUS PORTACAVAL-SHUNT IN PATIENTS WITH SEVERE CIRRHOSIS AND ACUTE VARICEAL HEMORRHAGE - LONG-TERM FOLLOW-UP
    CELLO, JP
    GRENDELL, JH
    CRASS, RA
    WEBER, TE
    TRUNKEY, DD
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1987, 316 (01) : 11 - 15
  • [8] PREVENTION OF RECURRENT BLEEDING IN CIRRHOTICS WITH RECENT VARICEAL HEMORRHAGE - PROSPECTIVE, RANDOMIZED COMPARISON OF PROPRANOLOL AND SCLEROTHERAPY
    FLEIG, WE
    STANGE, EF
    HUNECKE, R
    SCHONBORN, W
    HURLER, U
    RAINER, K
    GAUS, W
    DITSCHUNEIT, H
    [J]. HEPATOLOGY, 1987, 7 (02) : 355 - 361
  • [9] ROLE OF ENDOSCOPIC VARICEAL SCLEROTHERAPY IN THE LONG-TERM MANAGEMENT OF VARICEAL BLEEDING - A META-ANALYSIS
    INFANTERIVARD, C
    ESNAOLA, S
    VILLENEUVE, JP
    [J]. GASTROENTEROLOGY, 1989, 96 (04) : 1087 - 1092