ADSORPTIVE STRIPPING VOLTAMMETRIC DETERMINATION OF OFLOXACIN

被引：47

作者：

TAMER, A

机构：

[1] Department of Analytical Chemistry, Faculty of Pharmacy, Hacettepe University

来源：

ANALYTICA CHIMICA ACTA | 1990年 / 231卷 / 01期

关键词：

D O I：

10.1016/S0003-2670(00)86407-7

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The fluoroquinolone antibacterial agent ofloxacin was studied by adsorptive stripping voltammetry. Controlled interfecial accumulation of ofloxacin on a static mercury drop electrode in the hanging mercury drop mode provides high sensitivity. The linear concentration range was 0.079-197.5 μg ml-1 when using a 60-s preconcentration at -1 V vs. Ag/AgCl in Britton-Robinson buffer of pH 6.00. The detection limit of ofloxacin was 1 ng ml-1. The precision is excellent with a relative standard deviation of ca. 0.75% at a concentration of 0.848 μg ml-1. © 1990.

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页码：129 / 131

页数：3

相关论文

共 19 条

[1] STRIPPING VOLTAMMETRIC DETERMINATION OF SELENIUM IN BIOLOGICAL-MATERIALS BY DIRECT CALIBRATION [J].

ADELOJU, SB ;

BOND, AM ;

BRIGGS, MH ;

HUGHES, HC .

ANALYTICAL CHEMISTRY, 1983, 55 (13) :2076-2082

[2] DETERMINATION OF OFLOXACIN, A NEW OXAZINE DERIVATIVE IN HUMAN-SERUM, URINE, AND BILE BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].

CARLUCCI, G ;

GUADAGNI, S ;

PALUMBO, G .

JOURNAL OF LIQUID CHROMATOGRAPHY, 1986, 9 (11) :2539-2547

[3]

DESPLACES N, 1986, J ANTIMICROB CHEMOTH, V17, P93

[4] COMPARATIVE INVITRO ACTIVITIES OF CIPROFLOXACIN AND OTHER 4-QUINOLONES AGAINST MYCOBACTERIUM-TUBERCULOSIS AND MYCOBACTERIUM-INTRACELLULARE [J].

FENLON, CH ;

CYNAMON, MH .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1986, 29 (03) :386-388

[5]

GRASSI GG, 1986, INFECTION, V14, P300

[6] QUANTITATIVE-DETERMINATION OF OFLOXACIN, CIPROFLOXACIN, NORFLOXACIN AND PEFLOXACIN IN SERUM BY HIGH-PRESSURE LIQUID-CHROMATOGRAPHY [J].

GROENEVELD, AJN ;

BROUWERS, JRBJ .

PHARMACEUTISCH WEEKBLAD-SCIENTIFIC EDITION, 1986, 8 (01) :79-84

[7] DETERMINATION OF CAMAZEPAM AND BROMAZEPAM IN HUMAN-SERUM BY ADSORPTIVE STRIPPING VOLTAMMETRY [J].

HERNANDEZ, L ;

ZAPARDIEL, A ;

LOPEZ, JAP ;

BERMEJO, E .

ANALYST, 1987, 112 (08) :1149-1153

[8]

HOFFMAN H, 1982, FRESEN Z ANAL CHEM, V313, P625

[9] DETERMINATION OF SOME CEPHALOSPORINS BY DIFFERENTIAL PULSE POLAROGRAPHY AND LINEAR SCAN VOLTAMMETRY [J].

IVASKA, A ;

NORDSTROM, F .

ANALYTICA CHIMICA ACTA, 1983, 146 (FEB) :87-95

[10] FLUORINATED QUINOLONES - A REVIEW OF THEIR MODE OF ACTION, ANTIMICROBIAL ACTIVITY, PHARMACOKINETICS AND CLINICAL EFFICACY [J].

JANKNEGT, R .

PHARMACEUTISCH WEEKBLAD-SCIENTIFIC EDITION, 1986, 8 (01) :1-21