EFFECT OF LITHIUM-CARBONATE ON CIRCADIAN PERIODICITY IN HUMANS

被引：38

作者：

JOHNSSON, A

PFLUG, B

ENGELMANN, W

KLEMKE, W

机构：

[1] UNIV TUBINGEN,NERVEN KLIN,D-7400 TUBINGEN 1,FED REP GER

[2] UNIV TRONDHEIM,NLHT,INST PHYS,N-7000 TRONDHEIM,NORWAY

[3] UNIV TUBINGEN,INST BIOL 1,D-7400 TUBINGEN 1,FED REP GER

来源：

PHARMAKOPSYCHIATRIE NEURO-PSYCHOPHARMAKOLOGIE | 1979年 / 12卷 / 06期

关键词：

D O I：

10.1055/s-0028-1094638

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Five groups of two volunteers lived during four weeks under arctic summer conditions (Spitsbergen) isolated in huts, without time information. They received lithium carbonate or placebo. All showed free-run of their circadian temperature and activity/rest rhythms with periods longer than 24 hours. Under lithium carbonate, a period-lengthening effect can be shown. This could help to understand the prophylactic effect of lithium salts in manic-depressive episodes.

引用

页码：423 / 425

页数：3