DETERMINATION OF SULPHA-DRUGS WITH A PIEZOELECTRIC SENSOR

被引:14
作者
NIE, LH [1 ]
WANG, TQ [1 ]
YAO, SZ [1 ]
机构
[1] HUNAN UNIV,DEPT CHEM ENGN,NEW MAT RES INST,CHANGSHA 410082,PEOPLES R CHINA
关键词
D O I
10.1016/0039-9140(92)80011-2
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A piezoelectric sensor is used for the determination of sulpha-drugs, as pure substances and in their dosage forms, by an indirect micro method based on reaction of the sulpha-drug with bromine and reduction of the resultant N-bromoderivative with iodide to form iodine, which after extraction is monitored with a piezoelectric quartz sensor. The response of the sensor is linear from 2 x 10(-5) to 4 x 10(-4) M sulpha-drug.
引用
收藏
页码:155 / 158
页数:4
相关论文
共 6 条
[1]   AN APPLICATION OF A BROMINE REAGENT TO THE ASSAY OF SULFA DRUGS [J].
AMIN, D ;
SHABA, B .
MICROCHEMICAL JOURNAL, 1988, 37 (01) :30-35
[2]  
SITTIG M, 1981, HDB TOXIC HAZARDOUS, P75
[3]  
YAO SZ, 1988, ANAL CHIM ACTA, V215, P79
[4]  
1980, BRIT PHARMACOPOEIA, P432
[5]  
1980, US PHARMACOPOEIA, P744
[6]  
1985, CHINESE PHARMACOPOEI, V2, P637