PRODUCTION OF ISOANTIBODIES IN LITTERMATE DOGS AFTER ALLOGENEIC SKIN GRAFTING

被引:24
作者
COHEN, I
KOZAKI, M
机构
[1] Division of Immunology, Department of Microbiology and Immunology, Duke Medical Center, Durham, NC
[2] Department of Immunology, Hebrew University-Hadassah Medical School, Jerusalem
关键词
D O I
10.1097/00007890-196906000-00003
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Lymphocytotoxic isoantibodies were produced in littermate dogs following allogeneic skin grafting. Nonspecific positive reactions in the cytotoxicity test were eliminated if the rabbit serum used as a source of complement was absorbed with dog spleen. The alloantisera showed a pattern of reactions that may be used for typing of individual dogs for degrees of tissue compatibility. A correlation was observed between the graft rejection times and titers of antibodies. © 1969 by The Williams and Wilkins Co.
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页码:468 / &
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