DYSPLASTIC NEVI - AN ALTERNATIVE VIEW

被引:22
作者
COOK, MG [1 ]
FALLOWFIELD, ME [1 ]
机构
[1] ST GEORGE HOSP,DEPT HISTOPATHOL,LONDON SW17 0QT,ENGLAND
关键词
dysplastic naevus; melanocytic naevi; melanoma;
D O I
10.1111/j.1365-2559.1990.tb01056.x
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The diagnosis of dysplastic naevus is in danger of falling into disuse in response to the continuing dispute as to its definition. This review tries to show that the lesion can be defined using histological and clinical criteria but that the individual features are not, by themselves, peculiar to dysplastic naevi. They are shared, in varying degrees, by other benign melanocytic naevi and by melanoma. The significance of these similarities is explained on the basis of the maturation of ordinary naevi and degrees of deviation from that common path. The recognition of severely aberrant differentiation in the form of classic dysplastic naevus is worthwhile, since in the appropriate clinical context and particularly in association with a family history of melanoma, it confers a very high risk of developing melanoma. Copyright © 1990, Wiley Blackwell. All rights reserved
引用
收藏
页码:29 / 35
页数:7
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