NO ASSOCIATION BETWEEN RFLPS AT THE PORPHOBILINOGEN DEAMINASE GENE AND SCHIZOPHRENIA

被引：11

作者：

OWEN, MJ

MANT, R

PARFITT, E

WILLIAMS, J

ASHERSON, P

OMAHONEY, G

VANOS, J

LLEWELLYN, D

COLLIER, D

GILL, M

MCGUFFIN, P

机构：

[1] UNIV WALES COLL MED,INST MED GENET,CARDIFF CF4 4XN,S GLAM,WALES

[2] UNIV WALES COLL MED,DEPT MED BIOCHEM,CARDIFF CF4 4XN,S GLAM,WALES

[3] INST PSYCHIAT,GENET SECT,LONDON SE5 8AF,ENGLAND

来源：

HUMAN GENETICS | 1992年 / 90卷 / 1-2期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1007/BF00210756

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

An association study of restriction fragment length polymorphisms (RFLPs) in the porphobilinogen deaminase (PBGD) gene and schizophrenia was conducted. RFLPs detected by MspI, PstI, ApaLI and BstNI in intron 1 of the gene were studied in 49 patients and 79 controls. There were no significant differences between the groups in allele frequencies, genotype counts or haplotype distribution.

引用

页码：131 / 132

页数：2

共 12 条

[1]

COHEN J, 1977, STATISICAL POWER ANA

[2] A COMPARISON OF TESTS FOR HARDY-WEINBERG EQUILIBRIUM [J].